Genomic and Precision Medicine
Genomic and Precision Medicine: Cardiovascular Disease, Third Edition, focuses on the applications of genome discovery on the broad spectrum of cardiovascular disorders. Each chapter is organized for the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.
Over de auteurDr. Ginsburg is the founding Director of the Center for Applied Genomics & Precision Medicine in the Duke Institute for Genome Sciences & Policy. He is also Professor of Medicine and of Pathology at Duke University Medical Center, Professor of Biomedical Engineering at Duke Pratt School of Engineering, and Co-Director of the Duke Translational Medicine Institute. Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.
Inhoud1. Overview: A Systems Approach To Cardiovascular Medicine2. Application of Human Genome Information to Clinical Practice 3. Translating genome information into clinical practice and human health4. Big Data and Translational Bioinformatics Genomic and Personalized Medicine5. Health Risk Assessment and Family History6. Clinical Decision Support7. Overview of Policy, Ethical and Social Considerations8. Hypertension9. Lipoprotein Disorders10. Coronary Artery Disease and Myocardial Infarction11. The Vulnerable Plaque and Acute Coronary Syndromes12. Heart Failure13. Hypertrophic Cardiomyopathies14. Arrhythmias15. Hemostasis and Thrombosis16. Peripheral Arterial Disease17. Congenital Heart Disease18. Perioperative Genomics19. Stroke20. Novel Approaches to Cardiovascular Diagnostics21. Cardiovascular Pharmacogenomics22. Case Studies